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LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy

Breast cancer brain metastasis (BCBM) is a devastating disease. Radiation therapy remains the mainstay for treatment of this disease. Unfortunately, its efficacy is limited by the dose that can be safely applied. One promising approach to overcoming this limitation is to sensitize BCBMs to radiation...

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Detalles Bibliográficos
Autores principales: Chen, Yanke, Jiang, Ting, Zhang, Hongyi, Gou, Xingchun, Han, Cong, Wang, Jianhui, Chen, Ann T., Ma, Jun, Liu, Jun, Chen, Zeming, Jing, Xintao, Lei, Hong, Wang, Zhenzhen, Bao, Youmei, Baqri, Mehdi, Zhu, Yong, Bindra, Ranjit S., Hansen, James E., Dou, Jun, Huang, Chen, Zhou, Jiangbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962994/
https://www.ncbi.nlm.nih.gov/pubmed/33005030
http://dx.doi.org/10.1038/s41556-020-00586-6