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Epigenetic Changes Governing Scn5a Expression in Denervated Skeletal Muscle
The SCN5A gene encodes the α-subunit of the voltage-gated cardiac sodium channel (Na(V)1.5), a key player in cardiac action potential depolarization. Genetic variants in protein-coding regions of the human SCN5A have been largely associated with inherited cardiac arrhythmias. Increasing evidence als...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963191/ https://www.ncbi.nlm.nih.gov/pubmed/33803193 http://dx.doi.org/10.3390/ijms22052755 |