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Epigenetic Changes Governing Scn5a Expression in Denervated Skeletal Muscle

The SCN5A gene encodes the α-subunit of the voltage-gated cardiac sodium channel (Na(V)1.5), a key player in cardiac action potential depolarization. Genetic variants in protein-coding regions of the human SCN5A have been largely associated with inherited cardiac arrhythmias. Increasing evidence als...

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Detalles Bibliográficos
Autores principales: Carreras, David, Martinez-Moreno, Rebecca, Pinsach-Abuin, Mel·lina, Santafe, Manel M., Gomà, Pol, Brugada, Ramon, Scornik, Fabiana S., Pérez, Guillermo J., Pagans, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963191/
https://www.ncbi.nlm.nih.gov/pubmed/33803193
http://dx.doi.org/10.3390/ijms22052755