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Expanding the Spectrum of Pancreatic Cancers Responsive to Vesicular Stomatitis Virus-Based Oncolytic Virotherapy: Challenges and Solutions

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is a devastating malignancy with a poor prognosis and a dismal survival rate. Oncolytic virus (OV) is an anticancer approach that utilizes replication-competent viruses to preferentially infect and kill tumor cells. Vesicular stomatitis virus (...

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Detalles Bibliográficos
Autores principales: Holbrook, Molly C., Goad, Dakota W., Grdzelishvili, Valery Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963195/
https://www.ncbi.nlm.nih.gov/pubmed/33803211
http://dx.doi.org/10.3390/cancers13051171