Ibrutinib modulates Aβ/tau pathology, neuroinflammation, and cognitive function in mouse models of Alzheimer's disease

We previously demonstrated that ibrutinib modulates LPS‐induced neuroinflammation in vitro and in vivo, but its effects on the pathology of Alzheimer's disease (AD) and cognitive function have not been investigated. Here, we investigated the effects of ibrutinib in two mouse models of AD. In 5x...

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Detalles Bibliográficos
Autores principales: Lee, Hyun‐ju, Jeon, Seong Gak, Kim, Jieun, Kang, Ri Jin, Kim, Seong‐Min, Han, Kyung‐Min, Park, HyunHee, Kim, Ki‐taek, Sung, You Me, Nam, Hye Yeon, Koh, Young Ho, Song, Minseok, Suk, Kyoungho, Hoe, Hyang‐Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963331/
https://www.ncbi.nlm.nih.gov/pubmed/33709472
http://dx.doi.org/10.1111/acel.13332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963331/
https://www.ncbi.nlm.nih.gov/pubmed/33709472
http://dx.doi.org/10.1111/acel.13332

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