Mutation of daf‐2 extends lifespan via tissue‐specific effectors that suppress distinct life‐limiting pathologies

In aging Caenorhabditis elegans, as in higher organisms, there is more than one cause of death. C. elegans exhibit early death with a swollen, infected pharynx (P death), and later death with pharyngeal atrophy (p death). Interventions that alter lifespan can differentially affect frequency and timi...

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Detalles Bibliográficos
Autores principales: Zhao, Yuan, Zhang, Bruce, Marcu, Ioan, Athar, Faria, Wang, Hongyuan, Galimov, Evgeniy R., Chapman, Hannah, Gems, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963334/
https://www.ncbi.nlm.nih.gov/pubmed/33609424
http://dx.doi.org/10.1111/acel.13324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963334/
https://www.ncbi.nlm.nih.gov/pubmed/33609424
http://dx.doi.org/10.1111/acel.13324

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