Cargando…
Mutation of daf‐2 extends lifespan via tissue‐specific effectors that suppress distinct life‐limiting pathologies
In aging Caenorhabditis elegans, as in higher organisms, there is more than one cause of death. C. elegans exhibit early death with a swollen, infected pharynx (P death), and later death with pharyngeal atrophy (p death). Interventions that alter lifespan can differentially affect frequency and timi...
Autores principales: | Zhao, Yuan, Zhang, Bruce, Marcu, Ioan, Athar, Faria, Wang, Hongyuan, Galimov, Evgeniy R., Chapman, Hannah, Gems, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963334/ https://www.ncbi.nlm.nih.gov/pubmed/33609424 http://dx.doi.org/10.1111/acel.13324 |
Ejemplares similares
-
A fln-2 mutation affects lethal pathology and lifespan in C. elegans
por: Zhao, Yuan, et al.
Publicado: (2019) -
Shorter life and reduced fecundity can increase colony fitness in virtual Caenorhabditis elegans
por: Galimov, Evgeniy R., et al.
Publicado: (2020) -
Phosphatidylcholine Extends Lifespan via DAF-16 and Reduces Amyloid-Beta-Induced Toxicity in Caenorhabditis elegans
por: Kim, So-Hyeon, et al.
Publicado: (2019) -
Liangyi Gao extends lifespan and exerts an antiaging effect in Caenorhabditis elegans by modulating DAF-16/FOXO
por: Zeng, Liling, et al.
Publicado: (2019) -
Streptococcus thermophilus extends lifespan through activation of DAF-16-mediated antioxidant pathway in Caenorhabditis elegans
por: Desaka, Natsumi, et al.
Publicado: (2022)