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ATF3 drives senescence by reconstructing accessible chromatin profiles

Chromatin organization and transcriptional profiles undergo tremendous reordering during senescence. However, uncovering the regulatory mechanisms between chromatin reconstruction and gene expression in senescence has been elusive. Here, we depicted the landscapes of both chromatin accessibility and...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Zhang, Xuebin, Huang, Li, Guan, Yiting, Huang, Xiaoke, Tian, Xiao‐Li, Zhang, Lijun, Tao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963335/
https://www.ncbi.nlm.nih.gov/pubmed/33539668
http://dx.doi.org/10.1111/acel.13315