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Activation of CREB‐mediated autophagy by thioperamide ameliorates β‐amyloid pathology and cognition in Alzheimer’s disease

Alzheimer's disease (AD) is an age‐related neurodegenerative disease, and the imbalance between production and clearance of β‐amyloid (Aβ) is involved in its pathogenesis. Autophagy is an intracellular degradation pathway whereby leads to removal of aggregated proteins, up‐regulation of which m...

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Detalles Bibliográficos
Autores principales: Wang, Jiangong, Liu, Bin, Xu, Yong, Yang, Meizi, Wang, Chaoyun, Song, Mengmeng, Liu, Jing, Wang, Wentao, You, Jingjing, Sun, Fengjiao, Wang, Dan, Liu, Dunjiang, Yan, Haijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963336/
https://www.ncbi.nlm.nih.gov/pubmed/33682314
http://dx.doi.org/10.1111/acel.13333