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Re-evaluation of the mechanism of cytotoxicity of dialkylated lariat ether compounds
The cytotoxicity of dialkylated lariat ethers has been previously attributed to their ionophoric properties. Herein, we provide evidence that these effects are due to loss of membrane integrity rather than ion transport, a finding with important implications for the future design of synthetic ionoph...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963367/ https://www.ncbi.nlm.nih.gov/pubmed/33732448 http://dx.doi.org/10.1039/d0ra08494h |