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The Regulation of ROS- and BECN1-Mediated Autophagy by Human Telomerase Reverse Transcriptase in Glioblastoma

Glioblastoma (GBM) is the most common and aggressive malignant brain tumor with high morbidity and mortality. Human telomerase reverse transcriptase (hTERT), the catalytic subunit of human telomerase, is overexpressed in most cancers including GBM. It is well known that hTERT can compensate telomere...

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Detalles Bibliográficos
Autores principales: Ding, Xuelu, Nie, Ziyang, She, Zhaoyuan, Bai, Xue, Yang, Qiuhui, Wang, Feng, Wang, Fei, Geng, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963889/
https://www.ncbi.nlm.nih.gov/pubmed/33763172
http://dx.doi.org/10.1155/2021/6636510