Therapeutic Potential of RTA 404 in Human Brain Malignant Glioma Cell Lines via Cell Cycle Arrest via p21/AKT Signaling

BACKGROUND: Glioblastoma multiforme (GBM) is the most common malignant brain tumor in the world. Despite advances in surgical resection, radiotherapy, and chemotherapy, GBM continues to have a poor overall survival. CDDO (2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid), a synthetic triterpenoid, is an...

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Detalles Bibliográficos
Autores principales: Tsai, Tai-Hsin, Lieu, Ann-Shung, Wang, Yi-Wen, Yang, Sheau-Fang, Hsu, Yi-Chiang, Lin, Chih-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963900/
https://www.ncbi.nlm.nih.gov/pubmed/33763472
http://dx.doi.org/10.1155/2021/5552226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963900/
https://www.ncbi.nlm.nih.gov/pubmed/33763472
http://dx.doi.org/10.1155/2021/5552226

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