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CTLA-4 (+49A/G) Polymorphism in Type 1 Diabetes Children of Sudanese Population
Background Type 1 diabetes mellitus (T1DM) is an organ-specific T cell-mediated autoimmune disease, characterized by destruction of pancreatic islets. Cytotoxic lymphocyte antigen-4 ( CTLA-4 ) is a negative regulator of T cell proliferation, thus conferring susceptibility to autoimmunity. Aims Thi...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Georg Thieme Verlag KG
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7964255/ https://www.ncbi.nlm.nih.gov/pubmed/33748819 http://dx.doi.org/10.1055/s-0041-1723008 |