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CTLA-4 (+49A/G) Polymorphism in Type 1 Diabetes Children of Sudanese Population

Background  Type 1 diabetes mellitus (T1DM) is an organ-specific T cell-mediated autoimmune disease, characterized by destruction of pancreatic islets. Cytotoxic lymphocyte antigen-4 ( CTLA-4 ) is a negative regulator of T cell proliferation, thus conferring susceptibility to autoimmunity. Aims  Thi...

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Detalles Bibliográficos
Autor principal: Khalid Kheiralla, Khalid E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7964255/
https://www.ncbi.nlm.nih.gov/pubmed/33748819
http://dx.doi.org/10.1055/s-0041-1723008

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