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Long non-coding RNAs in lung cancer: implications for lineage plasticity-mediated TKI resistance
The efficacy of targeted therapy in non-small-cell lung cancer (NSCLC) has been impeded by various mechanisms of resistance. Besides the mutations in targeted oncogenes, reversible lineage plasticity has recently considered to play a role in the development of tyrosine kinase inhibitors (TKI) resist...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7965852/ https://www.ncbi.nlm.nih.gov/pubmed/33170304 http://dx.doi.org/10.1007/s00018-020-03691-9 |