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The transport pathway in the ABCG2 protein and its regulation revealed by molecular dynamics simulations

Atomic-level structural insight on the human ABCG2 membrane protein, a pharmacologically important transporter, has been recently revealed by several key papers. In spite of the wealth of structural data, the pathway of transmembrane movement for the large variety of structurally different ABCG2 sub...

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Detalles Bibliográficos
Autores principales: Nagy, Tamás, Tóth, Ágota, Telbisz, Ágnes, Sarkadi, Balázs, Tordai, Hedvig, Tordai, Attila, Hegedűs, Tamás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966132/
https://www.ncbi.nlm.nih.gov/pubmed/32979053
http://dx.doi.org/10.1007/s00018-020-03651-3