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Multi ‘Omics Analysis of Intestinal Tissue in Ankylosing Spondylitis Identifies Alterations in the Tryptophan Metabolism Pathway

Intestinal microbial dysbiosis, intestinal inflammation, and Th17 immunity are all linked to the pathophysiology of spondyloarthritis (SpA); however, the mechanisms linking them remain unknown. One potential hypothesis suggests that the dysbiotic gut microbiome as a whole produces metabolites that i...

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Detalles Bibliográficos
Autores principales: Berlinberg, Adam J., Regner, Emilie H., Stahly, Andrew, Brar, Ana, Reisz, Julie A., Gerich, Mark E., Fennimore, Blair P., Scott, Frank I., Freeman, Alison E., Kuhn, Kristine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966505/
https://www.ncbi.nlm.nih.gov/pubmed/33746944
http://dx.doi.org/10.3389/fimmu.2021.587119