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Repeat-Driven Generation of Antigenic Diversity in a Major Human Pathogen, Trypanosoma cruzi

Trypanosoma cruzi, a zoonotic kinetoplastid protozoan parasite, is the causative agent of American trypanosomiasis (Chagas disease). Having a very plastic, repetitive and complex genome, the parasite displays a highly diverse repertoire of surface molecules, with pivotal roles in cell invasion, immu...

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Detalles Bibliográficos
Autores principales: Talavera-López, Carlos, Messenger, Louisa A., Lewis, Michael D., Yeo, Matthew, Reis-Cunha, João Luís, Matos, Gabriel Machado, Bartholomeu, Daniella C., Calzada, José E., Saldaña, Azael, Ramírez, Juan David, Guhl, Felipe, Ocaña-Mayorga, Sofía, Costales, Jaime A., Gorchakov, Rodion, Jones, Kathryn, Nolan, Melissa S., Teixeira, Santuza M. R., Carrasco, Hernán José, Bottazzi, Maria Elena, Hotez, Peter J., Murray, Kristy O., Grijalva, Mario J., Burleigh, Barbara, Grisard, Edmundo C., Miles, Michael A., Andersson, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966520/
https://www.ncbi.nlm.nih.gov/pubmed/33747978
http://dx.doi.org/10.3389/fcimb.2021.614665