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Sites of chromosomal instability in the context of nuclear architecture and function

Chromosomal fragile sites are described as areas within the tightly packed mitotic chromatin that appear as breaks or gaps mostly tracing back to a loosened structure and not a real nicked break within the DNA molecule. Most facts about fragile sites result from studies in mitotic cells, mainly duri...

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Detalles Bibliográficos
Autores principales: Pentzold, Constanze, Kokal, Miriam, Pentzold, Stefan, Weise, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966619/
https://www.ncbi.nlm.nih.gov/pubmed/33219838
http://dx.doi.org/10.1007/s00018-020-03698-2