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Disorder in a two-domain neuronal Ca(2+)-binding protein regulates domain stability and dynamics using ligand mimicry

Understanding the interplay between sequence, structure and function of proteins has been complicated in recent years by the discovery of intrinsically disordered proteins (IDPs), which perform biological functions in the absence of a well-defined three-dimensional fold. Disordered protein sequences...

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Detalles Bibliográficos
Autores principales: Staby, Lasse, Kemplen, Katherine R., Stein, Amelie, Ploug, Michael, Clarke, Jane, Skriver, Karen, Heidarsson, Pétur O., Kragelund, Birthe B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966663/
https://www.ncbi.nlm.nih.gov/pubmed/32936312
http://dx.doi.org/10.1007/s00018-020-03639-z