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Disorder in a two-domain neuronal Ca(2+)-binding protein regulates domain stability and dynamics using ligand mimicry
Understanding the interplay between sequence, structure and function of proteins has been complicated in recent years by the discovery of intrinsically disordered proteins (IDPs), which perform biological functions in the absence of a well-defined three-dimensional fold. Disordered protein sequences...
Autores principales: | Staby, Lasse, Kemplen, Katherine R., Stein, Amelie, Ploug, Michael, Clarke, Jane, Skriver, Karen, Heidarsson, Pétur O., Kragelund, Birthe B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966663/ https://www.ncbi.nlm.nih.gov/pubmed/32936312 http://dx.doi.org/10.1007/s00018-020-03639-z |
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