Quercetin Attenuates Diabetic Peripheral Neuropathy by Correcting Mitochondrial Abnormality via Activation of AMPK/PGC-1α Pathway in vivo and in vitro

The AMPK/PGC-1α pathway-mediated mitochondrial dysfunction has been supposed to play a crucial role in pathogenesis of diabetic peripheral neuropathy (DPN). The present study investigated the neuroprotective potential of quercetin, a natural AMPK activator. Streptozotocin (STZ)-induced diabetic rats...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Song, Wei, Zhao, Bingjia, Xie, Jun, Sun, Qing, Shi, Xiaohu, Yan, Bin, Tian, Guoqing, Liang, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966726/
https://www.ncbi.nlm.nih.gov/pubmed/33746703
http://dx.doi.org/10.3389/fnins.2021.636172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966726/
https://www.ncbi.nlm.nih.gov/pubmed/33746703
http://dx.doi.org/10.3389/fnins.2021.636172

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