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Quercetin Attenuates Diabetic Peripheral Neuropathy by Correcting Mitochondrial Abnormality via Activation of AMPK/PGC-1α Pathway in vivo and in vitro
The AMPK/PGC-1α pathway-mediated mitochondrial dysfunction has been supposed to play a crucial role in pathogenesis of diabetic peripheral neuropathy (DPN). The present study investigated the neuroprotective potential of quercetin, a natural AMPK activator. Streptozotocin (STZ)-induced diabetic rats...
Autores principales: | Zhang, Qian, Song, Wei, Zhao, Bingjia, Xie, Jun, Sun, Qing, Shi, Xiaohu, Yan, Bin, Tian, Guoqing, Liang, Xiaochun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966726/ https://www.ncbi.nlm.nih.gov/pubmed/33746703 http://dx.doi.org/10.3389/fnins.2021.636172 |
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