Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen

Proteases are among the largest protein families and critical regulators of biochemical processes like apoptosis and blood coagulation. Knowledge of proteases has been expanded by the development of proteomic approaches, however, technology for multiplexed screening of proteases within native enviro...

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Detalles Bibliográficos
Autores principales: Uliana, Federico, Vizovišek, Matej, Acquasaliente, Laura, Ciuffa, Rodolfo, Fossati, Andrea, Frommelt, Fabian, Goetze, Sandra, Wollscheid, Bernd, Gstaiger, Matthias, De Filippis, Vincenzo, auf dem Keller, Ulrich, Aebersold, Ruedi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966775/
https://www.ncbi.nlm.nih.gov/pubmed/33727531
http://dx.doi.org/10.1038/s41467-021-21754-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966775/
https://www.ncbi.nlm.nih.gov/pubmed/33727531
http://dx.doi.org/10.1038/s41467-021-21754-8

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