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Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen
Proteases are among the largest protein families and critical regulators of biochemical processes like apoptosis and blood coagulation. Knowledge of proteases has been expanded by the development of proteomic approaches, however, technology for multiplexed screening of proteases within native enviro...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966775/ https://www.ncbi.nlm.nih.gov/pubmed/33727531 http://dx.doi.org/10.1038/s41467-021-21754-8 |