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Distinct DNA Methylation Patterns of Rheumatoid Arthritis Peripheral Blood and Synovial Tissue T Cells

OBJECTIVE: To study epigenetic patterns in T lymphocytes that accumulate in the rheumatoid arthritis (RA) synovium, we characterized DNA methylation of CD3(+) T cells in peripheral blood and synovial tissue in patients with RA and osteoarthritis (OA). METHODS: Genomic DNA of CD3(+) T cells was isola...

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Detalles Bibliográficos
Autores principales: Ai, Rizi, Boyle, David L., Wang, Wei, Firestein, Gary S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966880/
https://www.ncbi.nlm.nih.gov/pubmed/33544432
http://dx.doi.org/10.1002/acr2.11231