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Distinct DNA Methylation Patterns of Rheumatoid Arthritis Peripheral Blood and Synovial Tissue T Cells
OBJECTIVE: To study epigenetic patterns in T lymphocytes that accumulate in the rheumatoid arthritis (RA) synovium, we characterized DNA methylation of CD3(+) T cells in peripheral blood and synovial tissue in patients with RA and osteoarthritis (OA). METHODS: Genomic DNA of CD3(+) T cells was isola...
Autores principales: | Ai, Rizi, Boyle, David L., Wang, Wei, Firestein, Gary S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966880/ https://www.ncbi.nlm.nih.gov/pubmed/33544432 http://dx.doi.org/10.1002/acr2.11231 |
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