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A hierarchical and collaborative BRD4/CEBPD partnership governs vascular smooth muscle cell inflammation

Bromodomain protein BRD4 reads histone acetylation (H3K27ac), an epigenomic mark of transcription enhancers. CCAAT enhancer binding protein delta (CEBPD) is a transcription factor typically studied in metabolism. While both are potent effectors and potential therapeutic targets, their relationship w...

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Detalles Bibliográficos
Autores principales: Wang, Qingwei, Ozer, Hatice Gulcin, Wang, Bowen, Zhang, Mengxue, Urabe, Go, Huang, Yitao, Kent, K. Craig, Guo, Lian-Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966960/
https://www.ncbi.nlm.nih.gov/pubmed/33768129
http://dx.doi.org/10.1016/j.omtm.2021.02.021