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Lacto-N-biose synthesis via a modular enzymatic cascade with ATP regeneration
Human milk oligosaccharides (HMOs), the third most abundant solid component of human milk, are reported to be beneficial to infant health. The biosynthesis of lacto-N-biose (LNB), the building block for HMOs, suffers from excessive addition of cofactors and intermediate inhibition. Here, we develope...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967015/ https://www.ncbi.nlm.nih.gov/pubmed/33748718 http://dx.doi.org/10.1016/j.isci.2021.102236 |