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Evaluating the Impact of CYP3A5 Genotype on Post-Transplant Healthcare Resource Utilization in Pediatric Renal and Heart Transplant Recipients Receiving Tacrolimus

PURPOSE: CYP3A5 genotype is a significant contributor to inter-individual tacrolimus exposure and may impact the time required to achieve therapeutic concentrations and number of tacrolimus dose adjustments in transplant patients. Increased modifications to tacrolimus therapy may indicate a higher b...

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Detalles Bibliográficos
Autores principales: Pasternak, Amy L, Marshall, Vincent D, Gersch, Christina L, Rae, James M, Englesbe, Michael, Park, Jeong M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967030/
https://www.ncbi.nlm.nih.gov/pubmed/33746516
http://dx.doi.org/10.2147/PGPM.S285444