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Precision Surface Microtopography Regulates Cell Fate via Changes to Actomyosin Contractility and Nuclear Architecture

Cells are able to perceive complex mechanical cues from their microenvironment, which in turn influences their development. Although the understanding of these intricate mechanotransductive signals is evolving, the precise roles of substrate microtopography in directing cell fate is still poorly und...

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Detalles Bibliográficos
Autores principales: Carthew, James, Abdelmaksoud, Hazem H., Hodgson‐Garms, Margeaux, Aslanoglou, Stella, Ghavamian, Sara, Elnathan, Roey, Spatz, Joachim P., Brugger, Juergen, Thissen, Helmut, Voelcker, Nicolas H., Cadarso, Victor J., Frith, Jessica E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967085/
https://www.ncbi.nlm.nih.gov/pubmed/33747730
http://dx.doi.org/10.1002/advs.202003186