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Novel therapeutics for the treatment of hypertension and its associated complications: peptide- and nonpeptide-based strategies
The renin-angiotensin-aldosterone system (RAAS) is responsible for maintaining blood pressure and vascular tone. Modulation of the RAAS, therefore, interferes with essential cellular processes and leads to high blood pressure, oxidative stress, inflammation, fibrosis, and hypertrophy. Consequently,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967108/ https://www.ncbi.nlm.nih.gov/pubmed/33731923 http://dx.doi.org/10.1038/s41440-021-00643-z |