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Stress and Nasal Allergy: Corticotropin-Releasing Hormone Stimulates Mast Cell Degranulation and Proliferation in Human Nasal Mucosa

Psychological stress exacerbates mast cell (MC)-dependent inflammation, including nasal allergy, but the underlying mechanisms are not thoroughly understood. Because the key stress-mediating neurohormone, corticotropin-releasing hormone (CRH), induces human skin MC degranulation, we hypothesized tha...

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Detalles Bibliográficos
Autores principales: Yamanaka-Takaichi, Mika, Mizukami, Yukari, Sugawara, Koji, Sunami, Kishiko, Teranishi, Yuichi, Kira, Yukimi, Paus, Ralf, Tsuruta, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967145/
https://www.ncbi.nlm.nih.gov/pubmed/33803422
http://dx.doi.org/10.3390/ijms22052773