The Leukotriene Receptor Antagonist Montelukast Attenuates Neuroinflammation and Affects Cognition in Transgenic 5xFAD Mice

Alzheimer’s disease (AD) is the most common form of dementia. In particular, neuroinflammation, mediated by microglia cells but also through CD8+ T-cells, actively contributes to disease pathology. Leukotrienes are involved in neuroinflammation and in the pathological hallmarks of AD. In consequence...

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Detalles Bibliográficos
Autores principales: Michael, Johanna, Zirknitzer, Julia, Unger, Michael Stefan, Poupardin, Rodolphe, Rieß, Tanja, Paiement, Nadine, Zerbe, Horst, Hutter-Paier, Birgit, Reitsamer, Herbert, Aigner, Ludwig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967180/
https://www.ncbi.nlm.nih.gov/pubmed/33803482
http://dx.doi.org/10.3390/ijms22052782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967180/
https://www.ncbi.nlm.nih.gov/pubmed/33803482
http://dx.doi.org/10.3390/ijms22052782

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