Preclinical Evaluation of (99m)Tc-ZHER2:41071, a Second-Generation Affibody-Based HER2-Visualizing Imaging Probe with a Low Renal Uptake

Radionuclide imaging of HER2 expression in tumours may enable stratification of patients with breast, ovarian, and gastroesophageal cancers for HER2-targeting therapies. A first-generation HER2-binding affibody molecule [(99m)Tc]Tc-ZHER2:V2 demonstrated favorable imaging properties in preclinical st...

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Detalles Bibliográficos
Autores principales: Oroujeni, Maryam, Rinne, Sara S., Vorobyeva, Anzhelika, Loftenius, Annika, Feldwisch, Joachim, Jonasson, Per, Chernov, Vladimir, Orlova, Anna, Frejd, Fredrik Y., Tolmachev, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967187/
https://www.ncbi.nlm.nih.gov/pubmed/33803361
http://dx.doi.org/10.3390/ijms22052770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967187/
https://www.ncbi.nlm.nih.gov/pubmed/33803361
http://dx.doi.org/10.3390/ijms22052770

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