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Synthesis and Pharmacological In Vitro Investigations of Novel Shikonin Derivatives with a Special Focus on Cyclopropane Bearing Derivatives

Melanoma is the deadliest form of skin cancer and accounts for about three quarters of all skin cancer deaths. Especially at an advanced stage, its treatment is challenging, and survival rates are very low. In previous studies, we showed that the constituents of the roots of Onosma paniculata as wel...

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Detalles Bibliográficos
Autores principales: Kretschmer, Nadine, Hufner, Antje, Durchschein, Christin, Popodi, Katrin, Rinner, Beate, Lohberger, Birgit, Bauer, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967198/
https://www.ncbi.nlm.nih.gov/pubmed/33803437
http://dx.doi.org/10.3390/ijms22052774