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Design, Synthesis, and Evaluation of Novel 3-Carboranyl-1,8-Naphthalimide Derivatives as Potential Anticancer Agents

We synthesized a series of novel 3-carboranyl-1,8-naphthalimide derivatives, mitonafide and pinafide analogs, using click chemistry, reductive amination and amidation reactions and investigated their in vitro effects on cytotoxicity, cell death, cell cycle, and the production of reactive oxygen spec...

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Detalles Bibliográficos
Autores principales: Rykowski, Sebastian, Gurda-Woźna, Dorota, Orlicka-Płocka, Marta, Fedoruk-Wyszomirska, Agnieszka, Giel-Pietraszuk, Małgorzata, Wyszko, Eliza, Kowalczyk, Aleksandra, Stączek, Paweł, Bak, Andrzej, Kiliszek, Agnieszka, Rypniewski, Wojciech, Olejniczak, Agnieszka B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967199/
https://www.ncbi.nlm.nih.gov/pubmed/33803403
http://dx.doi.org/10.3390/ijms22052772