Silk Fibroin Nanoparticle Functionalization with Arg-Gly-Asp Cyclopentapeptide Promotes Active Targeting for Tumor Site-Specific Delivery

SIMPLE SUMMARY: Many tumor cell types overexpress integrins, a glycoprotein, on their cell membranes. The tripeptide motif Arg-Gly-Asp (RGD) is well-known for being recognized by the integrin superfamily members and can thus be used to actively target nanoparticles containing cytotoxic drugs directl...

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Detalles Bibliográficos
Autores principales: Bari, Elia, Serra, Massimo, Paolillo, Mayra, Bernardi, Eric, Tengattini, Sara, Piccinini, Filippo, Lanni, Cristina, Sorlini, Marzio, Bisbano, Giovanni, Calleri, Enrica, Torre, Maria Luisa, Perteghella, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967211/
https://www.ncbi.nlm.nih.gov/pubmed/33803385
http://dx.doi.org/10.3390/cancers13051185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967211/
https://www.ncbi.nlm.nih.gov/pubmed/33803385
http://dx.doi.org/10.3390/cancers13051185

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