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Metformin - its anti-cancer effects in hematologic malignancies
The main anti-diabetic effect of metformin mediated through stimulation of adenosine monophosphate (AMP)-activated protein kinase (AMPK) is the inhibition of hepatic gluconeogenesis and triggering glucose uptake in skeletal muscles. Additionally, some new pathways, besides the AMPK activation, were...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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PAGEPress Publications, Pavia, Italy
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967492/ https://www.ncbi.nlm.nih.gov/pubmed/33747367 http://dx.doi.org/10.4081/oncol.2021.514 |