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MicroRNA-383 promotes reactive oxygen species-induced autophagy via downregulating peroxiredoxin 3 in human glioma U87 cells

Peroxiredoxin 3 (PRDX3) is an abundant and effective enzyme, which aids in the removal of H(2)O(2) in the mitochondria, thereby inhibiting cell autophagy. PRDX3 is a target protein of microRNA (miRNA/miR)-383, the overexpression of which has been found to inhibit the growth of glioma cells. We hypot...

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Detalles Bibliográficos
Autores principales: Xu, Zhou, Zeng, Xingruo, Li, Mingchang, Liao, Jianming, Chen, Qianxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967820/
https://www.ncbi.nlm.nih.gov/pubmed/33747176
http://dx.doi.org/10.3892/etm.2021.9870