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Estrogen administration attenuates post-stroke depression by enhancing CREB/BDNF/TrkB signaling in the rat hippocampus

A previous study demonstrated that 17β-estradiol (E2), which is an antidepressant, can ameliorate post-stroke depression (PSD); however, the underlying mechanisms governing this remain largely unknown. Therefore, the present study developed a PSD model in rats, which was induced by left middle cereb...

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Detalles Bibliográficos
Autores principales: Jiang, Huigang, Xiao, Li, Jin, Kunlin, Shao, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967838/
https://www.ncbi.nlm.nih.gov/pubmed/33747172
http://dx.doi.org/10.3892/etm.2021.9850