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Chlorogenic acid enhances autophagy by upregulating lysosomal function to protect against SH-SY5Y cell injury induced by H(2)O(2)

Autophagy serves an important role in amyloid-β (Aβ) metabolism and τ processing and clearance in Alzheimer's disease. The progression of Aβ plaque accumulation and hyperphosphorylation of τ proteins are enhanced by oxidative stress. A hydrogen peroxide (H(2)O(2)) injury cell model was establis...

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Detalles Bibliográficos
Autores principales: Gao, Li-Juan, Dai, Yuan, Li, Xiao-Qiong, Meng, Shi, Zhong, Zhan-Qiong, Xu, Shi-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967846/
https://www.ncbi.nlm.nih.gov/pubmed/33747165
http://dx.doi.org/10.3892/etm.2021.9843