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4-phenylbutyric acid mediates therapeutic effect in systemic lupus erythematosus: Observations in an experimental murine lupus model

Impaired function of regulatory T cells (Tregs) contributes to the pathogenesis of systemic lupus erythematosus (SLE). Our previous study demonstrated aberrant responses of T lymphocytes to endoplasmic reticulum (ER) stress in patients with SLE. The present study investigated whether ER stress inhib...

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Detalles Bibliográficos
Autores principales: Choi, Yunjung, Jung, Ji-Hyun, Lee, Eun-Gyeong, Kim, Kyoung Min, Yoo, Wan-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967889/
https://www.ncbi.nlm.nih.gov/pubmed/33747192
http://dx.doi.org/10.3892/etm.2021.9891