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Status of CHEK2 and p53 in patients with early-onset and conventional gastric cancer

Gastric cancer (GC) is the fourth most common cause of cancer-associated death. Based on the age at diagnosis, GC is divided into early-onset GC (EOGC; ≤45 years) and conventional GC (CGC; >45 years). Mutations in the cell cycle checkpoint kinase 2 (CHEK2) and TP53 genes are associated with sever...

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Detalles Bibliográficos
Autores principales: Machlowska, Julita, Kapusta, Przemysław, Szlendak, Małgorzata, Bogdali, Anna, Morsink, Folkert, Wołkow, Paweł, Maciejewski, Ryszard, Offerhaus, G. Johan A., Sitarz, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967923/
https://www.ncbi.nlm.nih.gov/pubmed/33747205
http://dx.doi.org/10.3892/ol.2021.12609