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EIF5A2 enhances stemness of epithelial ovarian cancer cells via a E2F1/KLF4 axis

BACKGROUND: Ovarian cancer stem cells (OCSC), endowed with tumor-initiating and self-renewal capacity, would account not only for the tumor growth, the peritoneal metastasis, and the relapse, but also for the acquisition of chemotherapy resistance. Nevertheless, figuring out their phenotypical and f...

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Detalles Bibliográficos
Autores principales: Wang, Kun, Wang, Yiyang, Wang, Yuanjian, Liu, Shujie, Wang, Chunyan, Zhang, Shuo, Zhang, Tianli, Yang, Xingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967996/
https://www.ncbi.nlm.nih.gov/pubmed/33726845
http://dx.doi.org/10.1186/s13287-021-02256-2