Ruxolitinib induces apoptosis of human colorectal cancer cells by downregulating the JAK1/2-STAT1-Mcl-1 axis

Under pathological conditions, the Janus kinase (JAK)/STAT signaling pathway can regulate the proliferation, differentiation and migration of tumor cells, including colorectal cancer (CRC). CRC is the third major types of cancer among males and the second among females worldwide. In China, CRC is th...

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Detalles Bibliográficos
Autores principales: Li, Xia, Wang, Zhe, Zhang, Shengjie, Yao, Qinghua, Chen, Wei, Liu, Feiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967999/
https://www.ncbi.nlm.nih.gov/pubmed/33747209
http://dx.doi.org/10.3892/ol.2021.12613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967999/
https://www.ncbi.nlm.nih.gov/pubmed/33747209
http://dx.doi.org/10.3892/ol.2021.12613

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