Prenatal correction of IGF2 to rescue the growth phenotypes in mouse models of Beckwith-Wiedemann and Silver-Russell syndromes

Beckwith-Wiedemann syndrome (BWS) and Silver-Russell syndrome (SRS) are imprinting disorders manifesting as aberrant fetal growth and severe postnatal-growth-related complications. Based on the insulator model, one-third of BWS cases and two-thirds of SRS cases are consistent with misexpression of i...

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Detalles Bibliográficos
Autores principales: Liao, Ji, Zeng, Tie-Bo, Pierce, Nicholas, Tran, Diana A., Singh, Purnima, Mann, Jeffrey R., Szabó, Piroska E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968144/
https://www.ncbi.nlm.nih.gov/pubmed/33567274
http://dx.doi.org/10.1016/j.celrep.2021.108729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968144/
https://www.ncbi.nlm.nih.gov/pubmed/33567274
http://dx.doi.org/10.1016/j.celrep.2021.108729

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