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Omnitemporal choreographies of all five STIM/Orai and IP(3)Rs underlie the complexity of mammalian Ca(2+) signaling
Stromal-interaction molecules (STIM1/2) sense endoplasmic reticulum (ER) Ca(2+) depletion and activate Orai channels. However, the choreography of interactions between native STIM/Orai proteins under physiological agonist stimulation is unknown. We show that the five STIM1/2 and Orai1/2/3 proteins a...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968378/ https://www.ncbi.nlm.nih.gov/pubmed/33657364 http://dx.doi.org/10.1016/j.celrep.2021.108760 |