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Mechanism and Control of Meiotic DNA Double-Strand Break Formation in S. cerevisiae
Developmentally programmed formation of DNA double-strand breaks (DSBs) by Spo11 initiates a recombination mechanism that promotes synapsis and the subsequent segregation of homologous chromosomes during meiosis. Although DSBs are induced to high levels in meiosis, their formation and repair are tig...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968521/ https://www.ncbi.nlm.nih.gov/pubmed/33748134 http://dx.doi.org/10.3389/fcell.2021.642737 |