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Mechanism and Control of Meiotic DNA Double-Strand Break Formation in S. cerevisiae

Developmentally programmed formation of DNA double-strand breaks (DSBs) by Spo11 initiates a recombination mechanism that promotes synapsis and the subsequent segregation of homologous chromosomes during meiosis. Although DSBs are induced to high levels in meiosis, their formation and repair are tig...

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Detalles Bibliográficos
Autores principales: Yadav, Vikash Kumar, Claeys Bouuaert, Corentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968521/
https://www.ncbi.nlm.nih.gov/pubmed/33748134
http://dx.doi.org/10.3389/fcell.2021.642737