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SMARCB1/INI1-deficient tumors of adulthood

The SMARCB1/INI1 gene was first discovered in the mid-1990s, and since then it has been revealed that loss of function mutations in this gene result in aggressive rhabdoid tumors. Recently, the term “rhabdoid tumor” has become synonymous with decreased SMARCB1/INI1 expression. When genetic aberratio...

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Detalles Bibliográficos
Autores principales: Parker, Nathaniel A., Al-Obaidi, Ammar, Deutsch, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968524/
https://www.ncbi.nlm.nih.gov/pubmed/33796273
http://dx.doi.org/10.12688/f1000research.24808.2