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Protocatechuic acid attenuates cerebral aneurysm formation and progression by inhibiting TNF-alpha/Nrf-2/NF-kB-mediated inflammatory mechanisms in experimental rats

Our current research aims to examine whether protocatechuic acid (PCA) can be used as a therapeutic agent for the development of cerebral aneurysm (CA) and to elucidate the mechanisms behind this. We assessed the effects of PCA at 50 and 100 mg/kg on the activation of signaling pathways for tissue n...

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Detalles Bibliográficos
Autores principales: Xiao, Gang, Zhang, Mei, Peng, Xing, Jiang, Guangyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968537/
https://www.ncbi.nlm.nih.gov/pubmed/33817305
http://dx.doi.org/10.1515/biol-2021-0012